Clinical Trials Database
This Month's CME & CME News Updates

Evidence-Based Medicine

Psychometric Evaluation of a Patient-Rated Troubling Symptom Scale for
Generalized Anxiety Disorder Clinical Trials
By Gahan J. Pandina, Dennis A. Revicki, Leah Kleinman, Ibrahim Turkoz, Jasmanda Wu, Ramy Mahmoud, Georges M. Gharabawi

A Major Change of Prescribing Pattern in Absence of Adequate Evidence: Benzodiazepines Versus Newer Antidepressants in Anxiety Disorders
By Patricia Berney, MD, Demian Halperin, MD, Rodrigo Tango, MD, Isabelle Daeniker-Dayer, MD and
Pierre Schulz, MD

Developing and Testing Adaptive Treatment Strategies Using Substance-Induced Psychosis as an Example
By Ree Dawson,  Alan I. Green, Robert E. Drake, Thomas H. McGlashan, Bella Schanzer, Philip W. Lavori

Patterns of Pharmacotherapy and Treatment Response in Elderly Adults with Bipolar Disorder
By John L. Beyer, MD, Bruce Burchitt, PhD, Kenneth Gersing, MD, and K. Ranga R. Krishnan, MD

Clinical and Pharmacoeconomic Evaluation of Switch to Olanzapine in Veterans with Schizophrenia or Schizoaffective Disorder
By Lori L. Davis, MD, Marshall E. Cates, PharmD, BCPP, FASHP, Joette S. Lowe, PharmD, L. Charles Ward, PhD, Jeffrey D. Johnson, RN, BSN, Raela B. Williford, PharmD, Sandra M. Ambrose, MSN, Brandi L. Thomas, LCSW, and Terrell Michael Kashner, PhD, JD, MPH

Psychopharmacotherapy in Eating Disorders: A Systematic Analysis
By A. Riedl, MD, J. Becker, PhD, M. Rauchfuss, MD, and B.F. Klapp, MD

Concordance with Treatment Guidelines for Bipolar Disorder: Data from the Systematic Treatment Enhancement Program
for Bipolar Disorder
By Ellen B. Dennehy, PhD, Mark S. Bauer, MD, Roy H. Perlis, MD, Jane N. Kogan, PhD, and Gary S. Sachs, MD

Simple Options for Improving Signal Detection in Antidepressant Clinical Trials
By Craig H. Mallinckrodt, PhD, Adam L. Meyers, MS, Apurva Prakash, BA, Douglas E. Faries, PhD,
and Michael J. Detke, MD, PhD

Current Approaches to the Pharmacologic Treatment of Anxiety Disorders
David V. Sheehan, MD,MBA and Kathy Harnett Sheehan, PhD

Rational Antidepressant Selection: Applying Evidence-Based Medicine to Complex Real-World Patients
By Mark Zetin, MD, Cara T. Hoepner, RN, and Lynda Bjornson, PhD